First off, let me just say that Spine has improved leaps and bounds over the past year, and I can't thank the dev team enough for their dedication to making it the best it can be! Every new feature seems to make my life easier, and I know how easily the opposite could be true, so it's a testament to how much you listen to the community and to your careful versioning and testing.
That in mind, I thought I would share a very small suggestion, since every little bit helps Spine shine. When using manipulators involving large scales while zoomed in, I often find that I have trouble dialing in a specific position/rotation/scale through mouse movement alone, and usually resort to testing and revising numbers in the transform fields until I arrive at the ideal placement.
In Maya, where one often has objects of disparate scale in a scene and the manipulator occasionally struggles to adapt on the fly to the scale at which it believes you're currently trying to work, you can hold down the Ctrl key during any transformation operation to greatly increase the mouse input sensitivity. Instead of a 0.01 value change requiring only one pixel of mouse movement, it may require ten pixels in this mode, for instance.
It may just be owing to the fine resolution of my screen that I run into this issue as often as I do, but any sort of modifier key to temporarily increase sensitivity in this way seems like it would be consistently useful, if the implementation of such a thing wouldn't present undue difficulty. As it stands, pressing Ctrl during an operation appears to freeze it in place, but neither Alt nor Shift seem to do anything, so perhaps they're fair game, or some combination thereof.
While testing just now, I also noticed that I am able to set an object's transform to discrete positions via mouse input that can't seem to be arrived at using numerical input (due to rounding to the second decimal there), which adds further potential value to an increased sensitivity mode for those extra fine detail moments.
And here's the part where someone informs me that this already exists, hah!