370688 yazdı

But when the standby animation is played to the time point of changing the layer, unityspine will force the shader to change, resulting in the mouse hovering color failure.

What I think I understand is that
1) you are having an animation that is changing draw order, and
2) you change the shader when the mouse hovers over it.
Did I understand that correctly?

370688 yazdı

unityspine will force the shader to change

I think you mean that the submeshes are created in different order (spine-unity does not change shaders, it does not touch the shader or material that you set up) and you are replacing the material at a fixed index, which will not work since Materials at indices change order.
What you should do instead is use a CustomMaterialOverride that replaces one Material with another.

If you are using MaterialPropertyBlocks, then you should first check what material you are overriding and not use hardcoded indices like 0.

370688 yazdı

And...after Build ...is

You assign a shader programmatically here:

render.material.shader = Shader.Find("Spine/Outline/Skeleton");

Unity has no chance to know that it should include the shader in your build if there is nothing referencing it.
You have to add it to the Always included shaders:
https://docs.unity3d.com/2019.3/Documentation/Manual/class-GraphicsSettings.html

370688 yazdı

Hello, I didn't solve the problem, but I found it.

I think you did misunderstand how the material override concept works.

Your code does not work since you override the material with itself instead of with an outline material version. Furthermore you set the override in void Start() instead of when the mouse button is pressed:

ani.CustomMaterialOverride[render.sharedMaterial] = Material.Instantiate(render.sharedMaterial);// 

And when the mouse button is pressed, you modify the Renderer's material instead of setting the override:

if (Input.GetMouseButtonDown(0))
{
    render.material.shader = Shader.Find("Spine/Outline/Skeleton");
    ...
}

Here you should have set the custom material override, overriding the normal material with an outline version of the material.